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| Registros recuperados : 16 | |
| 2. |  | RODRIGUES, F. C.; SANTOS, A. T. L. dos; CRUZ, R. P. da; ALMEIDA-BEZERRA, J. W.; COUTINHO, H. D. M.; RIBEIRO, P. R. V.; BRITO, E. S. de; MORAIS-BRAGA, M. F. B.; OLIVEIRA, A. F. M. de. Antimicrobial activity, modulatory effect and phytochemical analysis of Sida galheirensis Ulbr. (Malvaceae). South African Journal of Botany, v. 147, 286-293, 2022.| Biblioteca(s): Embrapa Agroindústria Tropical. |
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| 3. | | AMARAL, W. DO; DESCHAMPS, C.; BIZZO, H. R.; PINTO, M. A. S.; SILVA, L. E. DA; BIASI, L. A.; FREITAS, T. S.; ROCHA, J. E.; CAMPINA, F. F.; COSTA, M. S.; BEZERRA, C. F.; COUTINHO, H. D. M. Essential Oil of Baccharis milleflora in the Atlantic Rain Forest of the Paraná State in Brazil: Chemical Composition and Biological Evaluation. In: AKHTAR, M. S.; SWAMY, M. K.; SINNIAH, U. R. (Ed.). Natural Bio-active Compounds: Production and Applications. Singapore : Springer Nature Singapore Pte Ltd., 2019. Cap. 22. v. 1 p. 599-608| Biblioteca(s): Embrapa Agroindústria de Alimentos. |
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| 4. | | BEZERRA, C. F.; ROCHA, J. E.; SILVA, M. K. N.; FREITAS, T. S.; SOUSA, A. K.; SANTOS, A. T. L. dos; CRUZ, R. P. da; FERREIRA, M. H.; SILVA, J. C. P. da; MACHADO, A. J. T.; CARNEIRO, J. N. P.; SALES, D. L.; COUTINHO, H. D. M.; RIBEIRO, P. R. V.; BRITO, E. S. de; MORAIS-BRAGA, M. F. Analysis by UPLC-MS-QTOF and antifungal activity of guava (Psidium guajava L.). Food and Chemical Toxicology, v. 119, p. 122-132, 2018.| Biblioteca(s): Embrapa Agroindústria Tropical. |
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| 5. | | LIMA, L. F. DE; ANDRADE-PINHEIRO, J. C.; FREITAS, M. A.; SILVA, A. I. DA; FONSECA, V. J. A.; SILVA, T. G. DA; SILVA, J. C. P. DA; LIMA, R. H. DE; SALES, D. L.; NEVES, R. P.; BRITO, E. S. de; RIBEIRO, P. R. V.; CANUTO, K. M.; COUTINHO, H. D. M.; SIYADATPANAH, A.; KIM, B.; MORAIS-BRAGA, M. F. B. Anti-Candida properties of Gossypium hirsutum L.: enhancement of fungal growth, biofilm production and antifungal resistance. Pharmaceutics, v. 14, n. 698, 2022. 18 p.| Biblioteca(s): Embrapa Agroindústria Tropical; Embrapa Alimentos e Territórios. |
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| 6. | | ARAÚJO, N. J. S.; SILVA, A. R. P.; COSTA, M. S.; FREITAS, T. S.; BARBOSA FILHO, J. M.; MATOS, Y. M. L. S.; MORAIS-BRAGA, M. F. B.; PEREIRA JUNIOR, F. N.; SILVA, C. A. P.; SOUZA, E. O.; RIBEIRO, P. R. V.; LACERDA, B. C. G. V. DE; ANDRADE, E. M. DE; COUTINHO, H. D. M.; ANDRADE-PINHEIRO, J. C. Chemical characterization UPLC-ESI-QToF-MSE, antibacterial and antibiofilm potential of Sarcomphalus joazeiro (MART.) Hauenschild. Food Bioscience, v. 50, 102066, 2022.| Biblioteca(s): Embrapa Agroindústria Tropical. |
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| 7. | | ANDRADE, J. C.; SILVA, A. R. P. DA; SANTOS, A. T. L. DOS; FREITAS, M. A.; MATOS, Y. M. L. S. DE; BRAGA, M. F. B. M.; BEZERRA, C. F.; GONÇALO, M. I. P.; VEGA-GÓMEZ, MARIA CELESTE; ROLÓN, M. S.; CORONEL MOLAS, C. C.; RIBEIRO, P. R. V.; BRITO, E. S. de; COUTINHO, H. D. M. Chemical composition, antiparasitic and cytotoxic activities of aqueous extracts of Ziziphus joazeiro Mart. Asian Pacific Journal of Tropical Biomedicine, Haikou, v. 9, n. 5, p. 222-226, May 2019.| Biblioteca(s): Embrapa Agroindústria Tropical. |
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| 8. | | BEZERRA, J. N.; GOMEZ, M. C. V.; ROLÓN, M.; CORONEL, C.; ALMEIDA-BEZERRA, J. W.; FIDELIS, K. R.; MENEZES, S. A. de; CRUZ, R. P. da; DUARTE, A. E.; RIBEIRO, P. R. V.; BRITO, E. S. de; COUTINHO, H. D. M.; MORAIS-BRAGA, M. F. B.; BEZERRA, C. F. Chemical composition, Evaluation of Antiparasitary and Cytotoxic Activity of the essential oil of Psidium brownianum MART EX. DC. Biocatalysis and Agricultural Biotechnology, v. 39, 102247, 2022.| Biblioteca(s): Embrapa Alimentos e Territórios. |
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| 9. | | COSTA, A. R.; SILVA, J. R. de L.; PEREIRA, P. S.; BEZERRA, J. W. A.; OLIVEIRA, M. A. S. de; RIBEIRO, P. R. V.; BRITO, E. S. de; DRUMOND, M. A.; CALIXTO JÚNIOR, J. T.; KAMDEM, J. P.; DUARTE, A. E.; BARROS, L. M.; COUTINHO, H. D. M. Influence of abiotic factors on phytochemical diversity of Anacardium occidentale L. Food Bioscience, v. 49, 101911, 2022.| Biblioteca(s): Embrapa Semiárido. |
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| 10. | | ANDRADE, J. C.; SILVA, A. M. DE O. E; SANTOS, A. T. L. DOS; FREITAS, M. A.; CARNEIRO, J. N. P.; GONÇALO, M. I. P.; SOUZA, A. Z. DE; FREITAS, T. S. DE; RIBEIRO, P. R. V.; BRITO, E. S. de; BRAGA, M. F. B. M.; COUTINHO, H. D. M. UPLC-MS-ESI-QTOF characterization and evaluation of the antibacterial and modulatory antibiotic activity of Ziziphus joazeiro Mart. aqueous extracts. South African Journal of Botany, Amsterdam, v. 123, p. 105-112, July 2019.| Biblioteca(s): Embrapa Agroindústria Tropical. |
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| 11. | | FREITAS, M. A. de; ANDRADE, J. C.; ALVES, A. I. S.; SANTOS, F. de A. G. dos; LEITE-ANDRADE, M. C.; SALES, D. L.; NUNES, M.; RIBEIRO, P. R. V.; COUTINHO, H. D. M.; MORAIS-BRAGA, M. F. B.; NEVES. R. P. Use of the natural products from the leaves of the fruitfull tree Persea americana against Candida sp. biofilms using acrylic resin discs. Science of the Total Environment, 703, art. no. 134779, 2020.| Biblioteca(s): Embrapa Agroindústria Tropical. |
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| 12. | | PINHEIRO, J. C. A.; SOUZA, C. E. S. DE; RIBEIRO, D. A.; SILVA, A. DE A.; SILVA, V. B. DA; SANTOS, A. T. L. DOS; FONSECA, V. J. A.; MACÊDO, D. G. DE; CRUZ, R. P. DA; BEZERRA, J. W. A.; MACHADO, A. J. T.; FREITAS, T. S. DE; BRITO, E. S. de; RIBEIRO, P. R. V.; COSTA, J. G. M. DA; COUTINHO, H. D. M.; KOWALSKA, G.; ROWINSKI, R.; KOWALSKI, R.; BRAGA, M. F. B. M. LC-MS analysis and antifungal activity of Turnera subulata Sm. Plants, v. 12, n. 415, 2023. 12 p.| Biblioteca(s): Embrapa Agroindústria Tropical; Embrapa Alimentos e Territórios. |
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| 13. | | SANTOS, J. F. S. dos; ROCHA, J. E.; BEZERRA, C. F.; SILVA, M. K. do N.; MATOS, Y. M. L. S. de; FREITAS, T. S. de; SANTOS, A. T. L. dos; CRUZ, R. P. da; MACHADO, A. J. T.; RODRIGUES, T. H. S.; BRITO, E. S. de; SALES, D. L.; ALMEIDA, W. de O.; COSTA, J. G. M. da; COUTINHO, H. D. M.; MORAIS-BRAGA, M. F. B. Chemical composition, antifungal activity and potential anti-virulence evaluation of the Eugenia uniflora essential oil against Candida spp. Food Chemistry, v. 261, p. 233-239, 2018.| Biblioteca(s): Embrapa Agroindústria Tropical. |
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| 14. | | FERNANDES, P. A. de S.; SILVA, J. C. P. da; SALES, D. L.; RIBEIRO, P. R. V.; BRITO, E. S. de; KERNTOPF, M. R.; DELMONDES, G. de A.; PINHEIRO, J. C. A.; SALAZAR, G. J. T.; BATISTA, F. L. A.; MAGALHÃES, F. E. A.; VEGA GOMEZ, M. C.; ROLÓN, M.; CORONEL, C.; RIBEIRO-FILHO, J.; BEZERRA, J. W. A.; SIYADATPANAH, A.; NISSAPATORN, V.; PEREIRA, M. de L.; COUTINHO, H. D. M.; BRAGA, M. F. B. M. Chemical constituents and biological activities of Croton heliotropiifolius Kunth. Antibiotics, v. 10, 1074, 2021.| Biblioteca(s): Embrapa Agroindústria Tropical. |
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| 15. | | BEZERRA, C. F.; ROCHA, J. E.; SILVA, M. K. do N.; FREITAS, T. S. de; SOUSA, A. K. de; CARNEIRO, J. N. P.; LEAL, A. L. A. B.; SANTOS, A. T. L. dos; CRUZ, R. P. da; RODRIGUES, A. S.; SALES, D. L.; COUTINHO, H. D. M.; RIBEIRO, P. R. V.; BRITO, E. S. de; COSTA, J. G. M. da; MENEZES, R. R. A. de; ALMEIDA, W. de O.; MORAIS-BRAGA, M. F. B. UPLC-MS-ESI-QTOF analysis and anti-Candida activity of fractions from Psidium guajava L. South African Journal of Botany, 131, pp. 421-427, 2020.| Biblioteca(s): Embrapa Agroindústria Tropical. |
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| 16. | | SANTOS, A. T. L. dos; CARNEIRO, J. N. P.; CRUZ, R. P. da; SALES, D. L.; PINHEIRO, J. C. A.; FREITAS, M. A. de; KERNTOPF, M. R.; DELMONDES, G. de A.; RIBEIRO, P. R. V.; BRITO, E. S. de; BATISTA, F. L. A.; MAGALHÃES, F. E. A.; PITA NETO, I. C.; BRAGA, M. F. B. M.; KOWALSKI, R.; KOWALSKA, G.; SZOPA, A.; BAJ, T.; COUTINHO, H. D. M. UPLC-MS-ESI-QTOF analysis and antifungal activity of aqueous extracts of Spondias tuberosa. Molecules, Basel, v. 28, n. 1, art. 305, Jan. 2023. 14 p.| Biblioteca(s): Embrapa Agroindústria Tropical; Embrapa Alimentos e Territórios. |
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| Registros recuperados : 16 | |
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 | Acesso ao texto completo restrito à biblioteca da Embrapa Agroindústria Tropical. Para informações adicionais entre em contato com cnpat.biblioteca@embrapa.br. |
Registro Completo
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Biblioteca(s): |
Embrapa Agroindústria Tropical; Embrapa Alimentos e Territórios. |
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Data corrente: |
02/01/2023 |
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Data da última atualização: |
29/02/2024 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
B - 1 |
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Autoria: |
LIMA, L. F. DE; ANDRADE-PINHEIRO, J. C.; FREITAS, M. A.; SILVA, A. I. DA; FONSECA, V. J. A.; SILVA, T. G. DA; SILVA, J. C. P. DA; LIMA, R. H. DE; SALES, D. L.; NEVES, R. P.; BRITO, E. S. de; RIBEIRO, P. R. V.; CANUTO, K. M.; COUTINHO, H. D. M.; SIYADATPANAH, A.; KIM, B.; MORAIS-BRAGA, M. F. B. |
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Afiliação: |
LUCIENE FERREIRA DE LIMA, University Regional of Cariri; JACQUELINE COSMO ANDRADE-PINHEIRO, University Regional of Cariri; MARIA AUDILENE FREITAS, University Federal of Pernambuco; ADRIELY IDALINA DA SILVA, University Federal of Pernambuco; VICTOR JUNO ALENCAR FONSECA, University Regional of Cariri; TAÍS GUSMÃO DA SILVA, University Regional of Cariri; JOSEFA CAROLAINE PEREIRA DA SILVA, University Regional of Cariri; ROSILAINE HONORATO DE LIMA, University Regional of Cariri; DÉBORA LIMA SALES, University Regional of Cariri; REJANE PEREIRA NEVES, University Federal of Pernambuco; EDY SOUSA DE BRITO, CNAT; PAULO RICELI VASCONCELOS RIBEIRO, CNPAT; KIRLEY MARQUES CANUTO, CNPAT; HENRIQUE DOUGLAS MELO COUTINHO, University Regional of Cariri; ABOLGHASEM SIYADATPANAH, Birjand University of Medical Sciences; BONGLEE KIM, Kyung Hee University; MARIA FLAVIANA BEZERRA MORAIS-BRAGA, University Regional of Cariri. |
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Título: |
Anti-Candida properties of Gossypium hirsutum L.: enhancement of fungal growth, biofilm production and antifungal resistance. |
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Ano de publicação: |
2022 |
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Fonte/Imprenta: |
Pharmaceutics, v. 14, n. 698, 2022. |
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Páginas: |
18 p. |
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DOI: |
https://doi.org/10.3390/pharmaceutics140406982022 |
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Idioma: |
Inglês |
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Conteúdo: |
(1) Background: Candida is a genus of yeasts with notable pathogenicity and significant ability to develop antimicrobial resistance. Gossypium hirsutum L., a medicinal plant that is traditionally used due to its antimicrobial properties, has demonstrated significant antifungal activity. Therefore, this study investigated the chemical composition and anti-Candida effects of aqueous (AELG) and hydroethanolic (HELG) extracts obtained from the leaves of this plant. (2) Methods: The extracts were chemically characterized by UPLC-QTOF-MS/MS, and their anti-Candida activities were investigated by analyzing cell viability, biofilm production, morphological transition, and enhancement of antifungal resistance. (3) Results: The UPLC-QTOF-MS/MS analysis revealed the presence of twenty-one compounds in both AELG and HELG, highlighting the predominance of flavonoids. The combination of the extracts with fluconazole significantly reduced its IC50 values against Candida albicans INCQS 40006, Candida tropicalis INCQS 40042, and C. tropicalis URM 4262 strains, indicating enhanced antifungal activity. About biofilm production, significant inhibition was observed only for the AELG-treated C. tropicalis URM 4262 strain in comparison with the untreated control. Accordingly, this extract showed more significant inhibitory effects on the morphological transition of the INCQS 40006 and URM 4387 strains of C. albicans (4) Conclusions: Gossypium hirsutum L. presents promising antifungal effects, that may be potentially linked to the combined activity of chemical constituents identified in its extracts. Menos(1) Background: Candida is a genus of yeasts with notable pathogenicity and significant ability to develop antimicrobial resistance. Gossypium hirsutum L., a medicinal plant that is traditionally used due to its antimicrobial properties, has demonstrated significant antifungal activity. Therefore, this study investigated the chemical composition and anti-Candida effects of aqueous (AELG) and hydroethanolic (HELG) extracts obtained from the leaves of this plant. (2) Methods: The extracts were chemically characterized by UPLC-QTOF-MS/MS, and their anti-Candida activities were investigated by analyzing cell viability, biofilm production, morphological transition, and enhancement of antifungal resistance. (3) Results: The UPLC-QTOF-MS/MS analysis revealed the presence of twenty-one compounds in both AELG and HELG, highlighting the predominance of flavonoids. The combination of the extracts with fluconazole significantly reduced its IC50 values against Candida albicans INCQS 40006, Candida tropicalis INCQS 40042, and C. tropicalis URM 4262 strains, indicating enhanced antifungal activity. About biofilm production, significant inhibition was observed only for the AELG-treated C. tropicalis URM 4262 strain in comparison with the untreated control. Accordingly, this extract showed more significant inhibitory effects on the morphological transition of the INCQS 40006 and URM 4387 strains of C. albicans (4) Conclusions: Gossypium hirsutum L. presents promising antifungal effects, that... Mostrar Tudo |
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Palavras-Chave: |
Antimicrobial resistance; Biofilm eradication; Erradicação do biofilme; Resistência antimicrobiana; UPLC-QTOF-MS/MS. |
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Thesagro: |
Gossypium Hirsutum; Malvaceae. |
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Categoria do assunto: |
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W Química e Física |
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Marc: |
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001 2153889
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100 1 $aLIMA, L. F. DE
245 $aAnti-Candida properties of Gossypium hirsutum L.$benhancement of fungal growth, biofilm production and antifungal resistance.$h[electronic resource]
260 $c2022
300 $a18 p.
520 $a(1) Background: Candida is a genus of yeasts with notable pathogenicity and significant ability to develop antimicrobial resistance. Gossypium hirsutum L., a medicinal plant that is traditionally used due to its antimicrobial properties, has demonstrated significant antifungal activity. Therefore, this study investigated the chemical composition and anti-Candida effects of aqueous (AELG) and hydroethanolic (HELG) extracts obtained from the leaves of this plant. (2) Methods: The extracts were chemically characterized by UPLC-QTOF-MS/MS, and their anti-Candida activities were investigated by analyzing cell viability, biofilm production, morphological transition, and enhancement of antifungal resistance. (3) Results: The UPLC-QTOF-MS/MS analysis revealed the presence of twenty-one compounds in both AELG and HELG, highlighting the predominance of flavonoids. The combination of the extracts with fluconazole significantly reduced its IC50 values against Candida albicans INCQS 40006, Candida tropicalis INCQS 40042, and C. tropicalis URM 4262 strains, indicating enhanced antifungal activity. About biofilm production, significant inhibition was observed only for the AELG-treated C. tropicalis URM 4262 strain in comparison with the untreated control. Accordingly, this extract showed more significant inhibitory effects on the morphological transition of the INCQS 40006 and URM 4387 strains of C. albicans (4) Conclusions: Gossypium hirsutum L. presents promising antifungal effects, that may be potentially linked to the combined activity of chemical constituents identified in its extracts.
650 $aGossypium Hirsutum
650 $aMalvaceae
653 $aAntimicrobial resistance
653 $aBiofilm eradication
653 $aErradicação do biofilme
653 $aResistência antimicrobiana
653 $aUPLC-QTOF-MS/MS
700 1 $aANDRADE-PINHEIRO, J. C.
700 1 $aFREITAS, M. A.
700 1 $aSILVA, A. I. DA
700 1 $aFONSECA, V. J. A.
700 1 $aSILVA, T. G. DA
700 1 $aSILVA, J. C. P. DA
700 1 $aLIMA, R. H. DE
700 1 $aSALES, D. L.
700 1 $aNEVES, R. P.
700 1 $aBRITO, E. S. de
700 1 $aRIBEIRO, P. R. V.
700 1 $aCANUTO, K. M.
700 1 $aCOUTINHO, H. D. M.
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700 1 $aKIM, B.
700 1 $aMORAIS-BRAGA, M. F. B.
773 $tPharmaceutics$gv. 14, n. 698, 2022.
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